Data Science is at the cutting edge of mental health research, traversing the study of the causes of mental disorders, their development, onset and experience of them, and presents opportunities to translate data driven insights to benefits for patients. The theme has rapidly developed in the last year in its capacity, know how, network, grants and in outputs. More and more work is being undertaken to understand the biological and psychosocial basis of mental disorders. Our collaborations are also expanding into multiple other units, universities and data science groups maximising the interdisciplinarity of this research theme collaborating with the Centre for Systems Modelling and Quantitative Biomedicine, the Institute of Applied Health Research and the Youth Advisory Group. The theme has had multiple high impact publications including in Lancet Psychiatry, Lancet Respiratory Medicine, Jama Psychiatry, Biological Psychiatry and Nature Medicine.